025: Genetic and epigenetic drivers of high risk blastemal Wilms tumors

HIPO Investigator:

Prof. Gessler

Prof. Pfister

Supported by: HIPO/NCT-POP

Entity: Wilms tumors

Publications:

Wegert J, et al.; TP53 alterations in Wilms tumor represent progression events with strong intratumor heterogeneity that are closely linked, but not limited to anaplasia. The Journal of Pathology: Clinical Research 2017

Wegert J et al.; Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors, Cancer Cell 2015

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